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Sexual contact, whether it is genital, oral, or anal, appears to be an extremely inefficient means of HCV transmission. In fact, many studies evaluating this route of transmission have failed to detect the presence of HCV in either the saliva, semen, or urine of HCV-infected people—except when these body fluids have been contaminated by the person's blood. However, it is important to emphasize that HCV has the potential to be transmitted through intimate contact if there are breaks in the skin or in the lining of the mouth, vagina, or anus. This may occur for a variety of reasons including the presence of active, bleeding herpes sores; an inflamed and infected prostate gland, known as prostatitis; or as a result of traumatic or rough sex, especially anal intercourse.
HCV has been detected with greater-than-average frequency among people who have a history of sexual promiscuity. While there is no exact definition for sexual promiscuity, one study published in the New England Journal of Medicine defines it as a "history of a sexually transmitted disease, sex with a prostitute, more than five sexual partners per year, or a combination of these." Of interest is that it appears to be easier for a man to transmit HCV to a woman than vice versa.
A person who is in a long-term monogamous relationship with an HCV-infected person rarely contracts this virus. Only approximately 2 percent (a range of 0 to 6 percent) of sexual partners of HCV-infected people also test positive for HCV. However, it is important to note that this statistic is based on indirect evidence only. Therefore, whether these people became infected through a sexual act or by another route is unclear. For example, people in long-standing relationships generally care for one another in times of illness or injury. During such times, HCV may be transmitted to the spouse or partner as blood-barrier precautions may not always be taken into consideration—even among the most cautious of couples.
Household Contact
Transmission of HCV among family members or other people living together may occur. This potentially can happen through the sharing of razors, toothbrushes, or any sharp instruments that carry HCV-infected blood. Therefore, it is crucial to keep all personal items, such as toothbrushes, in a separate part of the bathroom or specifically labeled. In this manner, the accidental use of a potentially HCV-infected household item will be decreased. The incidence of contracting HCV from accidental household contact in the United States is unknown. However, data from other countries indicate that it is low—approximately 4 percent.View Thread
JUST ME BEING ME ...
TIFFView Thread
To answer your first question;
My viral load has not been checked since treatment 12 years ago. No follow-ups were done either (only PCR from my GP.), and when I moved to BG , I again was unaware of the importance of regular viral load assay, and had only an annual PCR test done.
I shall have to go to the capital, Sofia to get my viral load checked very soon, and to see whether peg-interferon and ribavirin therapy is available under my existing UK ex-pat insurance status...
To answer your second question;
I was offered the option to go on interferon/ribavirin therapy for 6 months or for a year. i chose the full year option, because I thought that by pursuing this course, I might have a better chance of permanently eradicating the disease.
Prior to my treatment, no-one had had inf/rib therapy in my area (North of Scotland) and I presume that in those days, not enough data had been collected by local clinicians about the effects of shorter versus longer term therapies.
For instance, I knew more about positive response rates and treatment failure rates related to genotype than my gastroenterologist/ hepatologist.
Also (as an aside) I was aware of Japanese HCV therapy studies at the time, which noted the importance of avoiding cannabis during interferon therapy..
It (cannabis) interfered with a sustained response to interferon in the liver, and thus rendered the Japanese patients in this group non-responders.
Are you aware of this research Melissa?.. I have found little reference to it anywhere since, (actually none) and if the research is valid and robust, I would think it important that potential patients are made aware of this fact.
Neither my locum GP nor my hepatologist were aware of this research and thus, could not comment.
many thanks for your advice
richard
bulgariaView Thread
Her doctor thinks an antibiotic given by mouth caused the problem. Enzymes went up on her second day of taking Ceftin and Zithromax.
An ultrasound done a week after the onset of the elevated enzymes, on March 19, to investigate a cause for kidney failure subsequent to the liver problem, showed the following:
"The liver is mostly homogeneous in echotexture. There are multiple solid nodules in the liver. The largest measures 2.3 cm in the right lobe. There is no biliary duct dilatation. Impression: Multiple solid nodules in the liver suspicious for metastatic disease."
There has been no followup since the ultrasound. The thinking was to let her recover from a month in the hospital, but the vibe really seems to be, "she's old and has many medical problems, leave her be, do you want to know?, what would you do about the cancer anyway? etc."
I may be grasping and in denial here, but do granulomas ever follow drug-induced hepatitis and could they be mistaken for these solid nodules?
She has an appointment soon with her doctor. I may ask about repeating the ultrasound to see if the nodules are gone. I did read that granulomas will resolve after the offending medication is stopped. Would they resolve this quickly?
Thanks so much for reading.View Thread
I TELL FRIENDS IT IS SO EXHAUSTING BEING ME..LOL...
IF I WANT SOMETHING DONE IT IS DONE !!!!
TIFFView Thread
I have hep c for probably 15 yrs or so and have lived a completely normal life, got married, had a son, etc. There is a new treatment that involves 3 drugs. Pegintron (Interferon), Ribavirin and a Protese Inhibitor, either Boceprevir (Victrelis) or Telaprevir (Incivek). Treatment length will depend on a few things and your doctor will be able to better educate you on that. Make sure you get referred to a Hepatologist or a Gastroenterologist for further testing such as liver function and to get a genotype, which is basically a test to see which strain you have. You should get a liver biopsy too to see what condition your liver is currently in. Don't worry, it take only a few secs and is painless!
Treatment does have it's side effects. I did it about 6 yrs ago and was still able to work and maintain a normal life. The worst part for me was mild loss of hair and muscle aches. I did the treatment with just Pegintron and Ribavirin for nearly 48 weeks. I took a weekly injection of Pegintron and 6 pills a day of the Ribavirin. Unfortunately, I did not succeed with that treatment. Since new drugs have become available I am giving it another go round.
My advice to you is just calm down, get a good doctor, don't drink and take care of your body! You are very fortunate that you have Tri-care (my husband is military too) so the cost of treatment will be very cheap, if not free! The total cost can be somewhere around $70,000 or so!
Don't worry, you will be fine!!View Thread
I think Dr. Palmer gave you an excellent answer - if you are still concerned, ask for the test to be run - you have the right to ask your doctor for this, even if she told you not to worry.
Please try to manage your anxiety and guilt! I'm a mom, so I know all about over reacting! But it doesn't make getting through the day very easy!
Go give your daughter a big hug
Haylen
p.s. Check out our parenting forums here - you can chat with other moms and ask questions there about all kinds of parenting issues: WebMD Parenting CommunityView Thread
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