I have been fightingthis battle for 17 years with little to no results. I am at the point now thati will not go to a doctor for help because they don't know and I refuse to pay 35 dollars co pay for them to give me Zyrtec. I am not giving up just looking for answers myself. This has to be something internal that is out of balance. I have no allergies or any other conditions to speak of. I have tried diet changes, every anti-histimen mankind make with little effect. Today I ran across this artical and a ray of hope appered. http://www.steadyhealth.com/Delayed_Pressure_Urticaria__CURED_t240337.html I have scheduled an appointment and will get back to you when I can. If you read the comments one person suggested Gold Bond Uiltimate lotion. I just went to the store about 30 mins ago and tried it. I can say that the burning and itching stop after about five mins and the pain is going away too. I don't feel the constant heat I normaly feel but results and pending. Good luck and keep up the fight. View Thread