With hope of finding an alternative to "PREDISONE' I saw a new allegerist. After taking my history and testing, he stated that I would be a great candidate for Xolair. According to the doctor, what makes me a great candidate is my extremely high "IGE" levels (in the 1400+), and it has been in that range for a while. The only time it came down to 700 was when I was hospitalized for 7 days, in which my care consisted of 120 mg daily of steroids. I'm just scare of the unknown, the trade-offs. I have been trying to do my own research on this medicine to ensure that I am well informed on all the good and bad. Is there anyone out there who has been on Xolair for a while? Please share your experience. I've made a list of the damages "Prednisone" has done to my body and health and I cannot take anymore, no more. Swollen body, weight gain, constant stomach pain, irritable all time, border line diabetic, high blood pressure, now adrenal glands issues. I believe that if I do not make a stand now these issues will become permanent issues.