I can totally relate to everything you are saying and have been under all treatments possible. I had chronic hives for 11 years and tried everything possible. I have had test after tests to come up with negative results. I gave up caffeine, chocolate, and anything that had natural histamine in it. I finally asked my allergist to send me back to UCSF for another opinion since I hadn't been there in 7 years. The Dr I seen was amazing, he checked for chronic sinusitis by getting me a Catscan, of course that was negative. He did a biopsy and discovered I had some extra cells that were not usual for just hives and told me that I would benefit from Xolair. He suggested the shots to my allergist and we started the approval process. That was not easy they denied me but I appealed. After months I finally got approved. Clinical studies released on Feb 25,2013 concluded it was beneficial for chronic hives. I started my treatment a little over a month ago and have not had a single breakout. I was taking 11 antihistamine a day and now I take 1. If you have a really good Dr I would recommend the shots, your story sounds just like mine, I would call myself the elephant women.good luck keep me posted.View Thread
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