You are describing a problem that my husband has developed this year. He is a biochemist, organic chemist, medicinal chemist. So, we are reading up on this and trying quite a few solutions. My question for you guys is complicated... Who has elevated IgE counts? This is something you should be able to get with your blood work. Also, who has tried Sulfasalazine? Tom tried it, but it started to shut down his liver. He is fine now, but the wheels are beginning to return.