GSK's patent has already expired for Advair, but generic drug companies are having a hard time replicating the drug. I don't know when a generic equivalent will be available.
In order for a generic drug to be approved by the FDA, it has to have a bioequivalency equal to that of the name brand drug. That is, it has to be absorbed at the same rate and have the same safety and efficacy profile at the same dosages as the name brand drug. That would make the generic drug essentially equivalent to the name brand drug. Some people stick with a name brand drug because they know how they react to it and are scared to change. However, most people don't notice a difference between a name brand drug and its generic equivalent.
Asthma changes over time...sometimes it gets better and sometimes it gets worse. Ten years ago, I just used a rescue inhaler. Five years ago, I was on a laundry list of asthma medicines and had to take prednisone a couple times a year. I had horrible problems at night. Now I just take Singulair everyday, and use a low dose of Symbicort an hour or so before I go on a run. I rarely have to use my rescue inhaler. My symptoms also fluctuate over the course of a year, with my symptoms being the worst in the spring. During the spring I use Symbicort and Singulair every day, and use 3-4 puffs of my rescue inhaler before a run. So, to answer your question, it's perfectly normal for your asthma symptoms to change over time.View Thread
I gained a lot of weight over 6 months while taking another medication (not related to asthma). When my dosage was decreased, I was able to lose weight, but it was a struggle. Before I had gained all the weight, I ran marathons/half marathons and weight lifted a lot. Even while I was heavy, I started running again and changed my eating, and the weight (slowly) started to come off. It took a few weeks before I started to lose any weight. I lost an average of about 0.5 pounds (0.23 kgs) per week. It was a painfully slow process. My doctor changed my medicine to something else that didn't cause so much weight gain, and I started to lose about 1 pound (0.46 kg) per week, sometimes a little more.
I don't have any advice except keep plugging away. I know it's frustrating. I had a hard time dealing with my weight gain because I had always been thin and in shape. I can understand how it's hard to look in the mirror. Give it a little time because the weight loss isn't always immediate, and it might be slow going.
I think FEFV1 is the amount of air you can forcefully exhale in one second. The value is converted to a percent of normal, where normal is 80-120%. Yours is 52%, which is low. I don't know whether that's mild, moderate or severe.
If you're not seeing a specialist, such as an allergist, you should consider making an appointment with one. Regardless whether you're seeing a specialist, if you're dissatisfied with your treatment and are having issues (problems breathing, coughing a lot, waking up at night, problems exercising, etc) you need to discuss that with your doctor. Also, allergies can impact asthma a lot, so if you haven't been tested (and treated) for allergies, you may want to discuss that at your next appointment. All in all, I'd say your treatment plan is probably inadequate and should be re-evaluated.
Keep in mind, I'm not a doctor or healthcare professional of any kind. This is just my advice based on my experiences.
I'm at home with a cold today. It's not too bad, but I'm extremely tired and it's bothering my asthma a little bit.
I'm glad your appointment went well and things with your PT are going well.
It doesn't sound like your pain is decreasing much on its own. That sucks. Hopefully the pain starts to subside soon. When I hurt my IT band, my doctor told me that runner/triathlete types aren't very good at resting, so he was pretty explicit about what an acceptable level of pain was and told me not to do anything that causes my pain to exceed that level. I have to admit, I was pretty good at staying within his guidelines. It took a good 3-4 months before I was able to run pain free. Given that my injury wasn't as severe as yours, I'm thinking it's going to take longer for your hip to heal completely.
I can understand that the PT may have felt insecure treating someone who has some knowledge in the field, but he could've handled the situation much more gracefully. He could have at least given some thought to what you were telling him and then responding, instead of just listening to respond. I'm glad the PT you're seeing now isn't like that. Even my psychiatrist gives thought to what I say before she responds (even if it clashes with what she said). She leaves an open environment for me to say whatever I want, which is really nice because sometimes I don't agree with what she says, and she discusses it with me.
Yeah, my asthma isn't bothering me so much when I run anymore. I still take Singulair, though because it's grass season and it's always cat/dust season in the house. Once grass season ends, I'll try stopping Singulair. My cold is bothering my asthma a little bit. I've been wavering between low green and high yellow zones for the past few days.View Thread
I've been to PT a few times for various injuries (knee, hip, shoulder), but I've never experienced anything like you describe. I've never had a PT that insists he's the bomb and it's his way or the highway. All the PTs I've been too seemed to have my interests in mind (getting me back to my normal activity level in the shortest time possible and keeping me from getting injured again in the future). Maybe I've been lucky, I don't know. Anyway, hopefully things are going better with the other PT. I hope you're having less pain and you're getting your strength and ROM back.
I worked as a personal care attendant for a young women who had CP and was in a wheelchair. I hadn't had much experience with physical disabilities, but I noticed that a lot of people were uncomfortable around her and treated her like she was incapable. Like when we'd go out to eat at a restaurant, I swear they thought she couldn't read the menu or something. Working with her really opened my eyes.
For the past couple weeks I haven't been having as much problem with my asthma when I run. It's a nice change because running has been hard for the past 4 months. It's getting really hot now, but it has only been above 100 once or twice, so it's a relatively cool summer. Hopefully we don't get hit with a heat wave.View Thread
I don't go to yoga classes very often; I do most of my yoga at home. If I do go to a class, it's at my gym and the teachers don't give any one-on-one help. They just stay at the front of the room the entire time. I've seen progressions for poses on yogajournal.com, but not for all poses, just the more difficult ones. I do a lot of stretching poses (as opposed as to strength ones) because I'm not the most flexible person on this side of town.
Last week one of my rabbits died. He had an illness that was causing him to become paralyzed. We first noticed that he wasn't hopping quite right, then, within a week, it got to the point where he couldn't use his hind legs very well and had lost 20% of his body weight. We took him to the vet and she told us that it sounded like he had E. cumiculi, so we treated him for that and any pain. The vet basically told us he was would die once the disease moved up his spine and paralyzed his diaphragm, but the medicine could slow the progression. After 5 days of medicine he was a lot worse. He couldn't use his back legs at all, he became incontinent and was having problems using his front paws. At that point we decided that he was only going to get worse and the pain medicine wasn't helping him anymore, so we euthanized him. It was very sad
You gave a good explanation of what OT is and how it differs from PT. I've heard of OT before, but I didn't really know what it entailed. What piqued your interest in OT? Did you study OT as an undergrad (i.e. a major in OT), or is it like pharmacy school where you do some undergrad work then apply to a pharmacy program? What did you study as a grad student? I've always liked math and science a lot, so it was only natural that I pursued an engineering/science-related field. I changed my major many times, but they were all in related fields...engineering, physics, chemistry, computer science, etc.
I'm also a long distance runner. I had to stop running for a few years due to my asthma, and I was really excited when I was able to start running again. During certain times of the year, I have problems running. I have to slow my pace and sometimes have to stop and walk because I get so tired and have problems breathing. It gets a little frustrating, but I've learned to be patient with myself during those times. This year I decided to take a different approach to the situation by incorporating other endurance activities, such as swimming and biking, into my schedule. Incorporating those activities into my schedule has allowed me to increase my training volume and intensity because they don't trigger my asthma much. Even though I'm running less, I've noticed an improvement in my stamina.
Long term use of prednisone definitely has consequences. You probably wake up feeling like a zombie in the morning because you aren't breathing well at night. That probably affects everything you do for the entire day, including running. You didn't say whether you've tried other medicines like Symbicort, Advair or Dulera, which all have long-acting bronchodilators that last through the night so you can get a good sleep and wake up feeling better in the morning. If you haven't tried any of those medicines, it would be worthwhile to try one. Also, you didn't mention whether you were allergy tested. It's worth the effort because allergies can make asthma worse.
I'm sorry I can't give you any advice as to what I'd do if I were in your situation. I know I love running, and I was really bummed when I had to stop due to my asthma. It was part of my identity, and I felt like I was losing part of myself. I really think you're having problems with nocturnal asthma, which is affecting your entire day. Once you get that under control, I think you'll be fine.
I wish you the best of luck in finding a resolution.View Thread
It's actually pretty hard to find work from home contracts. Many employers want to know exactly what their employees are doing, hence, they make them come into the office. I've been lucky at finding work from home contracts, but I think my luck ran out. I wasn't able to find any work from home contracts, and I'm tired of the applying for jobs and interviewing scenario that comes up every few months when a contract ends. I came across a permanent position that seemed like a good fit so I sent in my resume, and they hired me. Fortunately, I haven't noticed much in the way of office politics so far.
What's the difference between a rehab therapist and a physical therapist? I'm assuming there's a difference because you refer to yourself a therapist in physical medicine and rehab, not a physical therapist.
When I do yoga stretches that involve hip flexibility, I really suck. My hips aren't very flexible. I don't know what kind of rotation this is, but when I cross my legs (ankle over knee), my right hip feels really tight. I can't rotate my right leg very well the other way, either. When I was in the Army and we had to qualify with our weapons, I couldn't get in the right firing position because my right leg wouldn't rotate inward very much. My foot would kind of be sticking in the air instead of resting on my left leg. It made it a little hard to balance myself when I fired my weapon.