While your TC is high. The LDL is fair (sub-optimal) as is non-HDL (TC-78) which has a goal of no more than 30 above the LDL goal.
And while the official goal of trig. is under150 some doctors recommend under 100.
Eating more good fats might help. That is mono & polyunstaterated oils. Olive oil, fatty fish, nuts, avocados. And eliminate as much simple carbs as you can, white flour, white rice, sugar and products made from them. Note that may commercial products have lots of added sugars .View Thread
But I don't know if what is reported in statin users is the same. They both have autoimmune responses. I don't understand all of the terms, but I saw a couple of things that make me think that they might be different.
Statins & Immune-Mediated Necrotizing Myopathy There are numerous case reports and small series that suggest that statins may be associated with idiopathic inflammatory myopathies in the traditional sense — dermatomyositis (DM), and polymyositis (PM), for example.[a title="Link: undefined">[5> There has been no conclusive proof of causality, and often the temporal relationship between the commencement of the statin and the development of DM or PM is the main reason a link between the two is suspected. In recent years, however, there has been mounting evidence pointing to an immune-mediated necrotizing myopathy associated with statin use that persists even in spite of statin withdrawal. Needham and colleagues were the first to report these findings.[a title="Link: undefined">[6> They investigated muscle pathology of eight patients with persistent myopathy despite statin withdrawal. All had myofiber necrosis. Only three had an inflammatory infiltrate, but MHC-I was upregulated. Following this case series,
New research suggests that statins appear to upregulate the expression of 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA), the major target of autoantibodies in patients who develop statin-associated autoimmune necrotizing myopathy. The results, according to investigators, provide a mechanistic link between an environmental trigger, statin therapy, and the development of a sustained autoimmune disorder that persists even after the drugs have been stopped. "In the vast majority of cases, in patients who develop muscle symptoms while taking statins, the symptoms resolve once you have the patient stop taking the statin, without any needed form of treatment," lead investigator Dr Andrew Mammen (Johns Hopkins Medical Institute, Baltimore, MD) told heartwire . "But there is a rare group of patients who develop a sustained autoimmune process that actually requires immunosuppressive therapy to treat. Otherwise, they continue to get worse and worse, with many of our patients coming into the clinic in wheelchairs, even after having been off the statin for months." Their findings are published in the December 2010 issue of Arthritis & Rheumatism.
Approximately 5% of individuals prescribed statins develop some sort of muscle side effects, such as cramping or muscle pain, that can lead to switching to another drug or stopping the medication altogether. Mammen stressed that the response resulting in necrotizing myopathy is extremely rare, doing a back-of-envelope calculation suggesting that one or two individuals per million per year develop the autoimmune disorder.
http://www.rxlist.com/pravachol-drug/indications-dosage.htm The recommended starting dose is 40 mg once daily. If a daily dose of 40 mg does not achieve desired cholesterol levels, 80 mg once daily is recommended. In patients with significant renal impairment, a starting dose of 10 mg daily is recommended.
http://www.rxlist.com/crestor-drug/indications-dosage.htm The dose range for CRESTOR is 5 to 40 mg orally once daily. The usual starting dose is 10-20 mg. ... The 40 mg dose of CRESTOR should be used only for those patients who have not achieved their LDL-C goal utilizing the 20 mg dose [see WARNINGS AND PRECAUTIONS>. ... In Asian patients, consider initiation of CRESTOR therapy with 5 mg once daily due to increased rosuvastatin plasma concentrations. The increased systemic exposure should be taken into consideration when treating Asian patients not adequately controlled at doses up to 20 mg/day.
http://www.rxlist.com/zocor-drug/indications-dosage.htm The usual dosage range is 5 to 40 mg/day. In patients with CHD or at high risk of CHD, ZOCOR can be started simultaneously with diet. The recommended usual starting dose is 10 or 20 mg once a day in the evening. For patients at high risk for a CHD event due to existing CHD, diabetes, peripheral vessel disease, history of stroke or other cerebrovascular disease, the recommended starting dose is 40 mg/day. ... Due to the increased risk of myopathy , including rhabdomyolysis , particularly during the first year of treatment, use of the 80-mg dose of ZOCOR should be restricted to patients who have been taking simvastatin 80 mg chronically (e.g., for 12 months or more) without evidence of muscle toxicity [see WARNINGS AND PRECAUTIONS>. Patients who are currently tolerating the 80-mg dose of ZOCOR who need to be initiated on an interacting drug that is contraindicated or is associated with a dose cap for simvastatin should be switched to an alternative statin with less potential for the drug-drug interaction. Due to the increased risk of myopathy, including rhabdomyolysis, associated with the 80-mg dose of ZOCOR, patients unable to achieve their LDL-C goal utilizing the 40-mg dose of ZOCOR should not be titrated to the 80-mg dose, but should be placed on alternative LDL-C-lowering treatment(s) that provides greater LDL-C lowering.View Thread
Portion control and moderation is probably the single "best diet".
One "trick" is to use smaller plates. That has shown to fake the body into being full with a little smaller meal.
Will Paleo is good diet it can be difficult in the extreme. Personally I lean a little more towards a Mediterranean diet with a little Paleo thrown in.
EX:eggs are good/eggs are bad, carbs are good/carbs are bad, etc...
In most cases the body generates all the cholesterol and the amount in diet has limited effect on the cholesterol in a blood test. Except for the US, most countries have relaxed their restriction on eggs. Eggs are a good source of low fat, high quality protein. 1 o 2 (and maybe more) a day can be part of a good diet.
Excess carbs are converted in the body and stored as fat.
For some people carbs seem to lead to insulation resistance and pee-diabetes. But with an HDL of 61, the doctor only wanting a 10 lb loss, and working backwards it appears that his triglycerides are about 70 which is good. So I don't think that is a significant problem for him.
But still you want to limit simple, refined carbs. White flours products, white rice, and sugar.
Whole grain products, whole wheat (but read the label whole wheat should be the first ingredient), brow rice, oatmeal, etc are better.
But a main guideline is to eat "real food". Most prepared and manufactured have excess carbs (often simple), bad fats, excess sodium, and lots of preservatives and additives.
Instead of packaged donuts or pastries, homemade whole wheat banana nut muffins.
Instead of bottle salad dressings some lemon juice or red wine vinegar and extra virgin olive oil.
His doc told him to lose 10 lbs,
10 lbs in 6 months is not much. That is only requires a reduction of about 230 calories a day.
And you did not indicate if he exercised. But even moderate amount of exercise, such as 20 minutes of brisk (3.5 miles/hr) each day a 150 lb person will burn about 86 calories a day.
And in any case the exercise, in it's own right helps reduce cholesterol and lower BP and has other health benefits. But to have the most effect more intense exercise is needed.
And bypass one 12 oz coke a day is another 126 calories.
Or one beer a day.
Or going from one cup of mash potatoes to 1/2 cup saves 110 calories.
Or eliminating one fancy drink that consists of a cup of sugar with a few drops of coffee (Starbucks) can reduce LOTS of calories.
Or even going from the extra extra large grande to small cup help a lot.
Actually no big change is needed, but with a lot of little changes it should be easy to lose twice that amount without feeling deprived.View Thread