An effective and inexpensive way of reducing venous pressure and cardiac output is by using drugs that reduce blood volume . These drugs (diuretics ) act on the kidney to enhance sodium and water excretion. Reducing blood volume not only reduces central venous pressure, but even more importantly, reduces cardiac output by the Frank-Starling mechanism due to the reduction in ventricular preload .
THIS ARTICLE DOES NOT SAY THAT AT ALL. It talks about RAISING HDL. In fact is says ;
More than 30 years ago, human epidemiological studies first revealed an association between HDL and risk for heart attack: the higher the levels, the lower the risk. Experiments in cells and mice further support the idea and suggest that HDL is protective because it may remove cholesterol from the sites where it can do damage. However, it has been difficult for researchers to prove conclusively that raising HDL levels is beneficial, primarily for two reasons. First, studies of human genetic diseases where individuals have very low HDL levels have not yielded definitive answers as to the impact on heart attack. And second, because there are currently no drugs that specifically elevate HDL levels, it has been difficult to prove in humans that such an intervention will lower heart attack risk.
Also it say; There is a well-studied connection between elevated LDL, often called the "bad cholesterol," and heart attack. Decades of research, including studies of genetic disorders in humans and the discovery of the LDL receptor and its role in cholesterol regulation, paved the way for the development of life-saving drugs known as statins. This work showed beyond any reasonable doubt that many different methods of reducing a person's LDL levels lower the risk of heart disease.
Now is this an article that you claim to prove it your ideas.
It say that lowering LDL with statins is LIFE SAVING and HDL levels are indicative of risk.View Thread
It is possible, but off hand I don't know of any that known for that.
But look at the package insert with the meds.
For my very limited experience it seems that the combination of lisinopril and HCTZ will lower HDL. And doing a search on that I did some some references to that fact. But a few others indicated the opposite.View Thread