The association between statin use and lower NAFLD prevalence grew stronger according to the duration of statin therapy (OR=0.76; 95% CI, 0.64-0.91 for 1 year of use). Researcher Edith M. Koehler,MD, gastroenterology and hepatology division, Erasmus MC University Hospital, in Rotterdam, Netherlands, told Healio.com that additional analysis has since been performed in patients who had used statins for more than 2 years, and that the association persisted.
"Often there's concern that statins may not be good for patients with NAFLD because they may elevate ALT," Koehler said. "Our findings [show> that statin use is not associated with an elevation of ALT, which suggests it's safe to prescribe to patients with or without NAFLD. It may even be good to prescribe statins to patients with NAFLD who don't have cardiovascular disease, because it may lower the prevalence of NAFLD."
Interesting, could be some good news for kidney patients;
Statin use may attenuate reductions in estimated glomerular filtration rate, leading to a modest delay in the progression of pathologic proteinuria among patients with chronic kidney disease, researchers reported in a recent meta-analysis.
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