Excellent article. Notice it said "perceived benefit"
This underscores the point I have been trying to drive home for years. The "benefit" from statins is only perceived in the mind of the consumer, based upon its ability to lower cholesterol, and consumer perception this somehow translates into lower risk for heart disease.View Thread
While I have never taken statins, I know friends who have. Several have complained of poor memory while taking statins.
Cholesterol is a major component of the brain. Here it serves in a process called synapses where nerve cells communicate with each other, aiding in memory.
Roughly 20% of the body's cholesterol supply is needed by the brain to function properly.
Understanding cholesterol's vital role in brain function helps us understand what could happen if we restrict its production. Thus it should come as no surprise that memory loss is a reported side effect with statin drugs.View Thread
While I have much respect for Dr. Nissen, I disagree.
Dr. Nissen is reporting the Relative Risk Reduction with statins, which makes the drug appear to more effective than it really is. Most statins have an Absolute Risk Reduction of around 1%. Meaning 100 people have to take the statin for just one person to benefit.
Side effects have been sadly under reported. Many patients quote their physician saying "Its not the statin causing your problems, your just getting older and have to accept a few muscle aches and pains." This brushing off of patient complaints has resulted in gross error in reporting the true impact of damage from these drugs.
As with any drug, its always important to weigh the risk and benefits. But until the public understands the difference between Relative Risk and Absolute risk, its easy for the drug companies to paint an overly positive picture of their drugs, and minimize the side effects. This is all a normal part of sales. Inflate the benefits- minimize the risks.
With statins its all about sales. Big corporations profiting from public perception that lowering serum cholesterol will somehow lessen risk of heart disease or stroke.
People who take statins don't live any longer than those who don't. These are not longevity drugs. When deciding the risk/ benefit ratio, don't look to them to add one single day to your life.View Thread
The brain is the organ most dependent upon cholesterol to function properly. It shouldn't be any wonder why these drugs have the capability of inducing memory loss and confusion. They block the substance needed for nerve synapses in the brain. Cholesterol.View Thread