I've been free of these terrible headaches for years now. Ever since taking an SSRI (serotonin reputable inhibitor)' specifically Sertraline HCL, a drug normally prescribed for anxiety/depression.
It's pretty benign in that it simply maintains a higher concentration of serotonin and clinical studies seem to support it's beneficial effects . (sorry no references).
So for me, no clusters in all the years I've been taking it. I find it a great alternative to Imitrex, which also works wonders but it's pretty heavy-duty!!!!!
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