Janumet is a single tablet that contains both Januvia and metformin. Each tablet contains 50mg of Januvia (half the daily dose) and either 500mg or 1,000mg of metformin. The combination (Janumet) costs almost the same as the Januvia alone, so the metformin, cheap enough by itself, is virtually free.
Understand, please, that I live in Costa Rica where the national health service provides only metformin for Type II diabetes management as well as injectable insulin. I buy the Janumet over the counter at a commercial pharmacy. We don't need a prescription for it, and many other meds, here.
In everyone's digestive tract, there are a number of "chemicals" (I'm being intentionally vague here) which interact with each other and which send chemical signals to other organs to participate in the digestive process.
As I get it from my endocrinologist, when carbohydrates get to where they are digested in the GI tract, a "chemical' is released to enable the digestion. That chemical triggers the release of a second chemical which, in turn, signals the liver to do whatever it needs to do to proceed with the digestion and, ultimately, the circulation of glucose in the bloodstream.
Januvia acts to interrupt this series of chemical secretions such that the carbohydrate is either not digested or else the liver doesn't do its part to process and circulate the resulting glucose.
The bottom line is that Januvia interrupts the digestion of carbohydrates, but it's only active in the presence of carbohydrates, and it only acts in the digestive tract. So there is no additional chemical burden placed on the liver.
All that said, let me tell you that there's a pretty good write-up about januvia on Wikepedia and it's probably clearer, too.View Thread
Yes, I am a Type II diabetic diagnosed in May of 2005 after a total thyroidectomy. It runs in my family.
I'm fairly active and do watch the glycemic index of what I eat. I also take Janumet 50/1,000 twice a day on the prescription of my endocrinologist. If you're not familiar, it's a combination of Januvia and metformin. The Januvia interrupts the digestion of carbohydrates but, as I get it from the endo, it's only active in the presence of carbs in the digestive tract.
On this regimen, my HbA1c are consistently in the 5.4 - 5.6 range, so I feel like I'm on a safe track.View Thread
Thank you very much, Dave and RS. This is exactly the information I've been looking for.
As a Type II diabetic, I have to look for any means to control my blood sugar, cholesterol and blood pressure. Oatmeal helps in all three venues.
I've lately read that a component of orange juice, when combined with oatmeal, suppresses the chemical breakdown of LDL and it's those broken-down components of LDL that actually form arterial plaques.
With that in mind, I've revised my daily breakfast menu. I now eat about 3/4 cup of uncooked whole oatmeal with 1/3 cup of mixed almonds and walnuts, a heaping tablespoon of raisins, and a tablespoon of cinnamon. I mix the dry ingredients, cover them with orange juice, and then add fresh fruit on top. All that goes into the refrigerator for an hour or so, but you can prepare it the night before.
I'm not losing any weight on this regimen, but my blood sugar and cholesterol are in great shape and I'm getting my daily ration of much of the stuff that's good for you.View Thread