As far as flare ups go I've noticed a couple triggers for myself. The weather especially barometric pressure changes of .7 kilopascals (kPa) during a 24hr perios, also big changes in humidity(20% increase or more in a day. But the biggest trigger I've found is stress.
As far as savella is concerned it is containdicated for drugs like Cymbalata and Lyrica. I don't know if these are like what your using so ask your pharmacist. Hope yhis helps.View Thread