I would not wish Effexor XR on my worst enemy. I was on it a few years ago and the withdrawal effects alone from it if you don't take it at exactly the same time each day are murder. It would send what felt like electrical pulses through my body whenever I would try to move and make my feet feel like they were going to give out from underneath me. It also severely affected my mood and behavior for the worst, causing both compulsive and impulsive behaviors and irrational thinking. Side effects are of course different in each person, but I would do some serious personal research on other medications before going with Effexor. There is a wealth of information available on the medications approved for Fibromyalgia treatment, the trick is to weigh the potential benefits against the highly possible negative side effects that any "mood altering" medications can cause.View Thread