Funny that you just posted this because I actually made the leap last Sunday and went off the Spiro. I finally went off because I am undergoing infertility treatments, and am taking some injectable gonadotropins in the hopes this will finally make me pregnant. I was worred the Spiro would decrease the effectiveness of the medications, and did not want to chance it. So, four days later my skin still looks great, but I think this is because these medications significantly increase my estrogen, and keep my PCOS androgens at bay. I am a very physically fit person and it took months for them to finally do an ultrasound to see if I really had PCOS -- which I did. I highly recommend that you request this so you can get the treatment you need sooner rather than later. Best of luck to you: )View Thread
You have been extremely helpful! Thank you for taking the time to reply. So, I found out it was not a miscarriage, rather my first menstrual cycle in years - which is great news. I must have had a false positive.
So, my RE put me on Letrozole 2.5mn days 3-7 ( I am on day 2). My question now is this: does spironolactone decrease the effectiveness of letrozole since once seems to increase estrogen (spiro) and one blocks estrogen (letrozole). Any insights would be greatly appreciated.
P.S. Yes, I have a PCOS diagnosis and also a hypothalamic amenorrhea diagnosis. I am an avid runner, and since this diagnosis I have decreased my running considerably.
Any infor re: letrozole and spiro would be greatly appreciated.
You have been such a huge help. I actually found out that it wasn't a miscarriage, rather my first menstrual cycle in years! Great news! My RE started me on Letrozole 2.5mg yesterday (day 3-7). I am now wondering if there are interactions with spironolactone and Letrozole? Does spiro decrease effectiveness of Letrozole?
By the way, yes I have been diagnosed with PCOS although I am not a typical PCOS. I am an avid runner and in a healthy weight range. I also have a diagnosis of Hypothalamic Amenorrhea, therefore I have cut back my exercise considerably.
Any thoughts on the spiro/letrozole question would be much appreciated.
You are an absolute angel, thank you so much for responding, aand what helpful information. I really appreciate it. I will absolutely discuss with my OB and will be super careful. You have put me at ease!View Thread
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