For now, there are enough data to support the recommendation for banning grapefruit and grapefruit juice altogether from the diets of those on certain cardiovascular medications. For laypersons who read my blog, I'll add the names under which these compounds are marketed. (For a more complete list, check abcnews.com.) They include:
Ticagrelor (Brilinta). Clopidogrel (Plavix)—in this case, it completely nullifies the effect of Plavix instead of exaggerating it, as in the other meds listed above.
In addition, there is an interaction with the heart-failure diuretic eplerenone (Inspra).
I note that sirolimus is also listed here, and I'm curious about patients with stents coated with sirolimus (the older Cypher stents), but I don't know of any data or case reports that directly address this issue.
Because most people do not have a problem with ACEinhibitors and in general they are very inexpensive.
Here is a comment from TheHeart, a sister forum of WebMD that is frequented by doctors. This is part of a discussion about using generics vs newer brand name drugs.
Initial therapy becomes long term maintinace for many... Although I recognize that collateral costs caused by generic ACE inhibitors may be substantial for patient's who experience cough; I disagree with Dr ... that such experiences should push us to regular initial use of brand name ARBs. The reported incidence of cough with Lisinopril is 4-9% (LexiComp Online 2011), if we start 100% of patients on a brand name ARB there are 91-96% of patients who have been done a disservice.
This report from Consumers Report discusses several of the different class of hypertensive drugs.
I have not seen that statistic, but I recently saw that healthy lifestyle will stop about 90% of the deaths from heart disease.
That is maintaining a healthy weight. No smoking. Limit alcohol to moderate amounts. East healthy - lots of options, but the main "ingredients" is to limit saturated fats and refined carbs (white flour products and sugars). And Exercise. Both aerobic and some resistance.
And will also help reduce diabetes and cancer.
By losing about 25 lbs and exercising - biking, brisk walking, swimming and gym - I as able to stop one BP med and go from 40 mg to 10 on the other one.View Thread