It's been awhile since my last post about my kidney biopsey results. I have still been experiencing severe left flank pain, blood in my urine, protein off, and on,and all the signs of "SLE clinical symptoms" My last RA visit showed my eGFR at 56(my last 5 blood tests for eGFR, have all been between 50 and 60). My Bun/Creatinine has been 12 or lower on blood work. According to my kidney biopsey results(This wasn't included on the report I had) I tested positive under Immunofluorescence microscopy for Mesangial regions stain for IgA 2+,IgM 2+, kappa(trace), lambda(trace) light chains in a granular pattern and segmental distribution. The walls of arterioles stain for C3 was 4+. Tubular casts stain for IgA 3+, kappa 3+, and lambda 2+ light chains. I also had IgG at 7.4 My RA factor came back as a 6, my Antiscleroderma-70 was a 4. My anti-DNA came back as a 5. My MCV, MCH, MCHC are all high, but RDW, is low. Can you help me with these results. I do not drink alcohol either, which I keep getting asked by these results. I also was told I have unspecified granuloma supeorior to my bladder dome and up my pertoneal walls. I kept being told, that these symptoms are in "my head", and there is nothing wrong with me. My nepherologist, said I have no "real", kidney issues. My health has went down rapidly in the last year. I lost my health insurance, and am at stand still. I am so confused. My PCP doc stands by his diagnoses with Polymyotosis, Dermamyotosis, and because my RA doc will not confirm Lupus(even though I have all the signs and symptoms), he is calling it unspecified myotosis. Can you please help? Sometimes I feel like ripping my kidneys out because the pain is sooo bad.View Thread
called my Kidney doctor to talk with her about my latest bloodwork. She said my low levels were caused by consuming alcohol. The only problem is, I don't drink. She said it might be my liver, I'm really confused now. She said my bloodwork is really confusing, because my A/G ratio is at a 3.0, which is high. I don't know. Then she asked if I've been tested for HIV, which I have several times, and that's all negative. Can autoimmune disease cause all these issues with my bloodwork? Can I rely on just my bloodwork test? Should I let specialist that have only seen me once go off my bloodwork, when it's never consistent?View Thread
Thanks John, you always seem to be able to explain things to where I can understand them. I guess I just don't know where to go from here. My PCP doc has been with me through the whole thing, and gets frustrated when I see a specialist, and they kind of pass it off after 1 test. I just wish there was more information out there about autoimmune disease and how your bloodwork is never normal, because you always, or at least I always have something going on with my body. My white blood cell counts are always high, in the 20 range, and my MCH is always high, around 36, and my FANA Staining patterns and Antinuclear Antibodies were both over 1:80 this last bloodwork, the time before they were equivical. I feel like my body is slowly dying, and there is nothing I can do, but ask questions. I just hope, someday soon, they will figure me out.View Thread
it's been 4 months since my last post about my kidney biopsey. i have been in the hospital with 4 times in the last 3 months with massive migraines and severe left kidney pain. I am still having severe left kidney pain, and blood in my urine. I was told by my Kidney doctor that this is a chronic condition, and there is nothing that can be done, because they are not sure what causes it, and there is no cure. Just pain medication. My kidney specialist said i no longer need to see her, because of this. My latest blood test showed my AST at 7, and my ALT at 6. My BUN/Creatinine level at 8. My eGFr was at 46, which has gone down, last three were 60, 58, 55, and now 46. I'm being told this is normal. I'm very confused. I believe my kidney biopsey results, and my last bloodwork, show I have a real issue..am i crazy for thinking this?View Thread
John, can you help me understand what my findings of my kidney biopsey means? Glomeruli that are globally sclerotic and wrinkled? paramesangial basement membranes that show corrugation? Subepithelial lucencies in capillary walls? I think my kidney doc thought I knew what all this means, but I have no clueView Thread
Thank you. I'm getting worse, and it seems like the latest symptoms with my kidneys are unbareable, pain, blood..etc. I feel like I'm just withering away with not a lot of answers. I just wish they could diagnose me, so I can move on with my life. Be put on some type of medication that will help me. I do know I have an autoimmune disease, a definate for polymyotisis, and a lupus maybe....I don't want to become a statistic, or a person who feels I should of done more. Thats why I'm asking questions. My father died of renal failure when he was 47. He only had one, because he gave one to his sister. i guess I'm getting traits from both sides of my family. Is kidney disease hereditary?View Thread
have been tentively diagnosed by my pcp doc with lupus. my blood tests, however, are either positive or equivical, so my Ra doc, who I've only seen once, says there is nothing wrong with me. i have high ana titiers, the butterfly rash, swelling in my feet and hands, and I am in severe pain and fatigue all the time. this has gone on since 2009. For the last 6 months, i have been experiencing severe left flank pain, and constant blood in my urine. I just had kidney a biopsey done. The results show i have moderate tubular atrophy, my arteries have intimal fibrosis and arterioles display muscular hypertrophy and hyalinization. I don't understand what these results mean, and was told by my kidney doctor I don't need to worry. i have two beautiful children. my mom passed away from sle, and breast cancer in 1985. i know there is something wrong with me, and I'm scared. what should I do.View Thread
Thank you so much for the reply. My kidney specialist said out of 14 glomeruli, i had 4 glomeruli that are globally sclerotic, and the remainder show wrinkling. i also have a few subepithelial lucencies in my capillary walls. She then went on to say my Paramesangial basement membranes show mild to moderate corrugation. She doesn't explain things well, but went on to say they don't know what causes this, and there was nothing they could really do, and I didn't need to see her again. she said that i would just have to live with the pain, and constant blood in my urine.View Thread
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