In my case at least, weight was not a factor. (I was a teen long before this recent, actually very recent, obesity epidemic arose.)
I weighed 120 pounds in high school, and I still weigh 120 pounds today. (I'm only 5'5" tall.)
So in my case I think that we need to chalk it up to 30 years of Type I diabetes and the slowly fluctuating blood glucose levels that come with that.
(BTW: The University of Minnesota began a study a few years ago searching for some genetic basis that might determine which diabetics get renal disease early, and which diabetics develop renal disease later or not at all. I participated in that study a decade ago, but I never found the final result of the data that was collected.)View Thread
It could be a lot of different things: minor "simple" cysts are very very common, and they are almost always just left alone since they very rarely cause any trouble. There are also a variety of tissue outgrowths that are benign, most are composed of a bit of fat and a few blood vessels (lipoma/myolipoma, angiomyolipoma). Harmless.
I probably would let them follow up with a doppler ultrasound since it would give them an idea of the amount of blood flowing through the lesion (cancers tend to be highly vascular, abnormally vascular).
It probably is nothing to worry about, but I'd follow up since a few types of renal cell carcinoma are very aggressive.View Thread
Yes, we always feel let down when a new drug turns out to have bad side effects.
But the newer FDA rules allow fast track approvals, which in the case of innovative lifesaving therapies might be a good thing. But the pharma companies take advantage of the newer rules to give them another few years to make bucks before their patents expire, even if a safer, more thoroughly tested drug is on the market.
In many cases, the severe adverse events only show up after patients have used a drug for several years. Sort of 'we're damned if we do, and we're damned if we don't.'View Thread
There have been a number of serious problems reported with these 'expanded dose' osteoporosis drugs, those that are dosed by injection every few months or years.
I suspect that most of these will get added black-box warnings, and some might even be withdrawn from the market.
The older drugs like alendronate/Fosamax, those that are taken by mouth once a week, have a somewhat better safety record, though long term use still has some serious potential side effects.View Thread