Cutaneous lupus can present in many different ways. Acute cutaneous lupus or lesions that are seen with sun exposure are most likely to be associated with systemic lupus. Subacute cutaneous lupus is usually associated with a positive SSA or SSB antibody, and chronic cutaneous lupus (including discoid lesions) are the least likely to progress to systemic lupus. Without knowing the details of your case it is hard for me to know if you have lupus. I have definitely seen lupus rashes that are raised or bumpy in the malar distribution. A skin biopsy with immunofluorescense could be helpful to determine if your rash is from lupus. A dermatology consult might be helpful.View Thread
In studies of DHEA - there was no effect on the levels of ANA or increase in complements. DHEA is a naturally occurring adrenal steroid which is stimulated in the adrenal gland which seems to help with lupus fatigue. There have been several small studies which led to a huge multi center study with 380 patients. And this study failed to show that DHEA really did that much. The study was published in 2002, and did not get FDA approval, however many clinical practices still continue to use it, especially in patients with a lot of mental fogginess and fatigue. So DHEA is not dead yet.View Thread
Lupus is usually diagnosed using the American College of Rheumatology criteria. If a person has 4/11 criteria for lupus they meet the ACR classification criteria. These criteria contain both clinical features and laboratory features. Just having a positive test does not give you lupus and there are many instances of false positive lab tests. Please consult with a rheumatologist to determine if you have lupus. Please look over some of our previous posts regarding diagnosis. All the best.
Many of us have observed that symptoms of lupus seem to improve after a patient goes on to hemodialysis. However, this is not a universal phenomenon and in some individuals lupus may remain active. In your daughter's situation, she may be having a hard time adjusting to the hemodialysis; she may have a condition called gastritis, or a stomach ulcer. Other causes of stomach pain need to be considered by her physicians as well. Hope she feels better. View Thread
There are few home remedies for a lupus rash that can help reduce the irritation and the itch considerably. Oatmeal is known to yield positive results as far as lupus rashes are concerned. Add ½ a cup of oatmeal to a tub of warm water. You will need to sit in this solution for a minimum of twenty minutes. Aloe vera juice could also be applied on the affected area to gain relief from the pain and to reduce the rashes. Cod liver oil, vitamin E oil and olive oil are excellent for lupus rashes. Apply a few drops of any of these oils on the affected area daily. Baking powder if dabbed to the rash also helps relieve local irritation that is caused by the rash. Drink plenty of water (6-8 glasses) and include a lot of green vegetables and fresh fruits into your daily diet. Always bear in mind, no matter how itchy the rash may be, one must take special care not to scratch them as that worsens the itchiness. [br>In terms of medications, corticosteroid creams can help the itchiness- 1% hydrocortisone cream is available over the counter, stronger corticosteroid creams are available by prescription. Anti-histamines like benadryl can be used at night time but as you mentioned, can cause significant drowsiness. In the daytime, "non-sedating" anti-histamines such as Claritin (loratadine), zyrtec (cetrizine) or allegra (fexofenadine) could be used. [br>All the best!View Thread
There are two methods used to test ANA's. The first method is by immunofluorescence (IIF) which is reported as a ratio. Usually anything over 1:80 is considered a significant result. The second method is by enzyme-linked immunosorbent assay (ELISA) which is reported an absolute number or in the way you mentioned such as 3 . ELISA is increasingly being used because of the ease of testing through automation and no need of a skilled operator in the lab. However, the accuracy of ELISA testing has been questioned. Please see a previous post from me about ANA testing below.