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One risk factor is a mutation (alteration) in a gene known as BRAF, which may play a part in causing melanoma. In one study, this mutated gene was found in two-thirds of the melanoma cells analyzed, and typically about half of melanoma patients have this defective gene. BRAF is called a "switch" gene, because it turns on by itself and stays turned on, allowing the cells to keep growing and dividing. Mutations in this gene can lead to uncontrolled cell growth and cancer.
Another risk is a sunburn in the area when you were younger. Just one blistering sunburn as a child more than doubles your risk of melanoma. To keep yourself safe from the sun, follow The Skin Cancer Foundation's Prevention Guidelines (http://www.skincancer.org/Guidelines/ ).
The good news is that when caught early most melanomas are very treatable. Monitoring your skin for changes on a monthly basis is recommended. Learn how to perform a self exam by visiting http://www.skincancer.org/Self-Examination/ .
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Learn more about the history and evolution of Mohs micrographic surgery in this informative article from the 2011 edition of The Skin Cancer Foundation Journal at http://digitaleditions.sheridan.com/publication/?i=70417&p=61.View Thread

AKs are not life-threatening, but should be diagnosed and treated in the early stages. If left untreated, aggressive AKs have the potential to progress into squamous cell carcinoma, a potentially serious type of skin cancer, which is occasionally life-threatening. Therefore, it is important to report any suspicious skin lesions to your dermatologist. According to the American Cancer Society, One in six people will develop an AK in their lifetime. Since cumulative sun exposure increases with age, older people are more likely to develop AKs. Patients with multiple AKs have a lifetime risk of progression to squamous cell carcinoma of 5% to 9%.
Common treatment options are cryosurgery (freezing the lesion with liquid nitrogen), topical chemotherapy creams, photodynamic therapy, chemical peels and laser resurfacing therapy. Your dermatologist will help you decide which option is best for you.View Thread

- Superficial Spreading Melanoma
- Lentigo Maligna
- Acral lentiginous melanoma
- Nodular melanoma
Early melanomas (Stages I and II) are localized, and more advanced melanomas (Stages III and IV) have spread (metastasized) to other parts of the body. There are also subdivisions within stages.
Once the disease has advanced to Stage IV, melanoma cells have traveled through the body via the bloodstream or lymph vessels, going far from the original tumor site. They may have reached distant lymph nodes or invaded the internal organs. This can be in addition to or instead of in-transit metastases or local spread to the regional lymph nodes. In local forms of the disease, the metastases can reach skin or subcutaneous tissue more than 2 cm from the primary tumor, but not beyond the regional lymph nodes.
When distant metastases are suspected, they can be traced by scans of the chest, head, abdomen, and pelvis with a CT (computed tomography) scan in which special X-ray equipment and a computer program show a cross-section of body tissues or organs; an MRI (magnetic resonance imaging) scan that uses a magnet instead of X rays to create a map of the patient's body and brain; and by PET (positron emission tomography), an evolving radiographic technique. For PET scanning, radioactive sugar, the basic carbohydrate utilized by the body for energy, is injected intravenously into the patient. This sugar may be taken up rapidly by any melanoma cells that are present.
You can learn more about the stages of melanoma at http://www.skincancer.org/melanoma/Stages-of-Melanoma.html .View Thread

You are the best defense against skin cancer. Perform monthly skin examinations of your entire body and watch for unusual marks or changes to your skin. We recommend regular skin exams by a dermatology professional and even more frequently if you have been diagnosed with a skin cancer.View Thread

As a dermatologist and skin cancer expert in the Sunshine state, I encounter many former "sun worshipers" that have been diagnosed with skin cancer. Were you a frequent "sun worshiper"? How has this changed your life? Do you now use daily sun protection with a broad-spectrum sunscreen?
Reply and share your experience.View Thread
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