I have been on this med for years... I started on small doses and worked my way up to higher doses.. I am currently up to 150 mgs and it is not working. My doctor just put me on Topamax and I have an appt with a specialist in two weeks. I have gained 20+ lbs on this med this time. I have been off this med before and lost weight when I did. It increases your appetite. When it works, it works great.View Thread