My son is 15, and has had nightly migraines for the past year. They are so severe that he has been unable to attend school. We have tried amitriptyline. Topomax, combo of amitriptyline and topomax, indomethican, acupuncture, chiropractor, and sleep studies. He has also taken high dosages of magnesium oxide and b2. We have had 2 hospital stays to try to break the cycle, but they were short lived. I am desperate to find some relief for him, as he is becoming quite depressed. Any suggestions? His neurologist calls him one of his toughest cases ever.View Thread