One of the causes of atrophy is an excessive amount of apoptosis of cells. Apoptosis is a form of cell death. I suspect apoptosis is the main cause of brain atrophy in the case of chronic and/or age related disorders.
Low doses of diphenhydramine (Benadryl) inhibit apoptosis!
There is also reason to believe that low dose Benadryl is an effective treatment for MS in general.
you need to learn about the "mito cocktail" of vitamins and supplements. There are some resources but everyone's cocktail is a bit different so there is a lot of trial and error. Google "mito cocktail" and you'll see
read here about low dose Benadryl and statin damage: