There are levels on some over-the-counter medication that I am sure may be a bit on the conservative side, regarding mg/day. My experience has been that the Medical Community, and I agree with this, would rather err on the side of conservatism than cause a fatality; especially when something is within control. Tolerances may be built toward these medications and I am a great fan of homeopathy and naturopathy, and use a topical I know works. Regarding controlled substances, I believe the same holds true, in that the Rx doseage will be first conservative. You are correct in that is subjective, different for each indiviual and situation, type injury, etc. Again, tolerance is built, which is why I like the stuff I use.View Thread