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October 4, 2010
Dear Healthcare Professional:
On April 5, 2010, the U.S. Food and Drug Administration (FDA) approved Purdue Pharma
New Drug Application for a reformulation of 80mg OxyContin
® (oxycodone hydrochloride
controlled-release) Tablets. Purdue elected to reformulate OxyContin to be bioequivalent to
the original formulation and in an effort to make the tablet more difficult to manipulate for
the purpose of intentional misuse and abuse, however, there is no evidence that the
reformulation of OxyContin is less subject to misuse, abuse, diversion, overdose, or addiction.
Since introducing reformulated OxyContin to the market on August 9, 2010, Purdue has
received reports that some patients are encountering diffi culties with swallowing
the reformulated tablet. Purdue encourages you to counsel your patients on
appropriately taking this medication and to remind them that:
"022 OxyContin Tablets should be taken one tablet at a time, with enough water to
ensure complete swallowing immediately after placing in the mouth
"022 Multiple tablets should not be swallowed together
"022 Tablets should not be dampened, soaked, licked, or otherwise wet prior to
placing them in the mouth for immediate swallowing
Regards RBView Thread

October 4, 2010
Dear Healthcare Professional:
On April 5, 2010, the U.S. Food and Drug Administration (FDA) approved Purdue Pharma
New Drug Application for a reformulation of 80mg OxyContin
® (oxycodone hydrochloride
controlled-release) Tablets. Purdue elected to reformulate OxyContin to be bioequivalent to
the original formulation and in an effort to make the tablet more difficult to manipulate for
the purpose of intentional misuse and abuse, however, there is no evidence that the
reformulation of OxyContin is less subject to misuse, abuse, diversion, overdose, or addiction.
Since introducing reformulated OxyContin to the market on August 9, 2010, Purdue has
received reports that some patients are encountering diffi culties with swallowing
the reformulated tablet. Purdue encourages you to counsel your patients on
appropriately taking this medication and to remind them that:
"022 OxyContin Tablets should be taken one tablet at a time, with enough water to
ensure complete swallowing immediately after placing in the mouth
"022 Multiple tablets should not be swallowed together
"022 Tablets should not be dampened, soaked, licked, or otherwise wet prior to
placing them in the mouth for immediate swallowing
View Thread

AVN is usually caused by 3 different things the first one is blunt force trauma which is what happened to you. 2nd is alcoholism and the 3rd and most common is long term prednisone (steroid) use, there are some other factors that can cause AVN but these are the most common.it's a progressive disease that keeps coming back so if you replace one joint there is a good chance you will do it again. There are only a couple of treatments that can be done and replacement is the most effective and relieves most of your pain the second is a bone graft which is crazy to me, I've checked it out and core decompression which has about a 5% chance of working and is a waste of time and money about $10,000 I did it outpatient and it just sped up my problem in my left hip..Feel better RBView Thread


I have avascular necrosis requiring both hip replacements and both shoulder replacements at 40 yrs old.View Thread




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