We applied Vectra3D to our 12 year old Lhasa Apso at 3:00 one afternoon. By 8pm she was running around the yard like she was on steroids. She did not sleep at all that night, and was pacing, twitching, and seemingly upset all night. Her heart was racing and she her body felt too warm. I called our vet in the morning, and they told us to wash her with Dawn dishwashing soap, as it is a good de-greaser, and remove as much of the product as we could. I will NOT be using this product again, and will look for a natural alternative for killing ticks and fleas. I have heard that brewer's yeast can be helpful, and will investigate.View Thread