dacipota4ever:I have been diagnosed with PCOS as well. The cramps that i experiance get just as bad as yours at times especially right before i start my period. Tylenol, Ibeprofin, Asprin, Motrin, Miodol, and Advil doesnt work at all for me. The two things i have found that have done a little something for me at times are Goodie Powders and Pamprin. If you try those make sure none of them have Asprin in them. I cant remember if they do or not. My doctor also proscibed me Hopicit (bottle is faded but i think thats what it says) in big letters on the bottle it is called BUTALB-ACETAMIN-CAFF. That is short for butalbital acetaminophen caffeine. Ask your doctor if you can try that. It may work. I hope you find something that will help. I know how it is to get major cramps like that and are unable to find relief at times. I hope all works out well for you.View Thread