My father-in-law, who is 72 or so, is suffering from a lot of clotting/bleeding from his bladder. He's had...
Posted by An_252982
My father-in-law, who is 72 or so, is suffering from a lot of clotting/bleeding from his bladder. He's had surgery 3 or 4 times to caurterize the bladder wall wounds, which are from Radiation about two or three years ago for Prostate cancer. He loses a lot of blood, then they give him more blood transfusions, then surgery, then Hyperbolic chambers. It's an ongoing process. He's failing and we don't know what to do. Where can he go next? UPenn to a Urology Oncologist? A cancer center? Advice, please!View Thread
Had a diagnosis of prostrate cancer after a biopsy. Gleason was 3+4 and PSA 12.7. Pre-surgery MRI and bone...
Posted by An_252964
Had a diagnosis of prostrate cancer after a biopsy. Gleason was 3+4 and PSA 12.7. Pre-surgery MRI and bone scan were clear of cancer, so a radial prostatectomy was performed with wide margins of tissue removed. The margins were clear (lymph nodes and other tissue) and there was no cancer outside the capsule of the prostrate. The surgeon recommended PSA testing and had a good report. Nine days after surgery I had a DVT episode which called for an ultrasound and eventually a CTscan to diagnose a lymphocele. The local urologist said that this CTscan (taken 4 weeks after the one at Vanderbilt) has spots on the bones??? I will not be back with my Vanderbilt doctor for four more weeks. I will be sending them the film ahead of that visit. Anyone else ever have this happen or is this perhaps a machine malfunction? The local urologist seemed puzzled by it.View Thread
I have questions about the meaning of these positive margins in particular . 1. APEX: Positive , focal , right side. What does focal mean with this margin ? 2. PERIPHERAL: Positive , right lateral toward apex in area of capsular incision. What does capsular incision mean with this margin ? Could this positive margin be an artifact ?View Thread
I had an aggressive prostate cancer at age 45. Now, almost 6 years following surgery, I have detachable levels of PSA at 0.19, slowly rising about 0.03 every 3-6 months. Doctor doing a wait and see method for next 3-6 months to see if level rises above 0.20 then plans to radiate old prostate area to kill off any active cells that may have attached themselves prior to previous surgery. Your thoughts?,View Thread
Had a biopsee in Feb.an came back pos.Gl. score of 6.psa 24.6. When in doubt? Had a one done in July an came back neg. Showed Doc. first report an he replyed that he didn't know how but said that it was most likely pos.basiced on first report?? Can two biopsee be dif.???View Thread
Like cancer does benign prostate tissue left behind after surgery cause the psa to rise or just cause the psa to become detectable without any increase ? This may be the case with me ( nerve sparing ) if my psa is stable at this low level ( 0.028 - 0.03 ) 1 year after surgery !View Thread
Hi Mike, - Let me respond to the questions that you have posed and to which the answers, in my opinion, have been confusing, to say the least.
For years, the Clinical Standard for "undetectable PSA" in routine monitoring situations following surgery has been LESS THAN 0.1 ng/ml, which is usually depicted as < 0.1 on Laboratory Reports. Although there are RARE individual situations where this may not be the standard used by an individual Physician, it remains the most widely accepted definition of "undetectable PSA', BY FAR.
So, in nearly every case of ROUTINE monitoring following surgery this still remains the criteria for the use of the term, "undetectable" in reference to post-treatment PSA. The figures you cite in your Posts are all below this Standard if the decimal points are accurately reflected.
Obviously, accuracy of the decimal point placement is critically important in judging PSA significance in the post-treatment monitoring, as is the understanding of the metric system in use. The 0.1 ng/ml threshold, referred to above, represents 1/10th of a BILLIONTH of a Gram of PSA found in 1 milliliter of blood. The finding of 0.01 ng/l is 1/100th and 0.001 is 1/1000th of a BILLIONTH of a gram, so these are "minute" (my-noot) amounts of PSA that are present.
Again, anything below 0.1 ng/ml (<0.1) is therefore considered clinically undetectable in routine monitoring of low and/or moderate risk, post-treatment results.
The < icon always identifies the term "LESS THAN" and reflects the fact that any PSA present, IF ANY, is BELOW the known reliability of the assays (the test's) known sensitivity and so is reported thusly.
As long as PSA results remain below the 0.1 ng/ml level, you usually need not initiate any aggressive secondary treatment, in low or moderate risk patients. I hope this helps your understanding. - John@newPCa.org (aka) az4peaks
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