I don't know for sure how much of a dosage I received. I seem to be in less pain in my arm, which had been bothering me for months. My main concern is, this is the first biologic drug I received, and according to the mfg. instructions, it should only be used if the other biologics don;t work, so I am on the fence as to continue it or not. I am in a study group, so it is free. I have no idea what the prescriptions cost. Maybe the side effects will only last for a couple infusions, till your body gets used to it. If you are usually in a lot of pain without the drug, I would continue using it. How long were you on the other two drugs? I appreciate you responding to me. It is nice to know someone is on the same drug, especially when it is new on the market. I go again for another infusion on June 27th. I am anxious to see how it will turn out. I am also going to talk with my rheumy about my concerns. Will post again when I know more. PretzeladyView Thread
I was currently put in a study comparing Actemra with another Biologic drug. The purpose of this study is to compare the the way the two drugs act on the cardiovascular illnesses. My concern is, everything I have read about Actemra says it should be used only if the TNF biologic drug doesn't work. This is also stated on the Actemra website. This drug has just been FDA approved in the United States and I believe it has been on the market for about two years. If anyone has been on this drug or has any information about it, I would appreciate hearing from you. My main concern is if it is safe to take without taking a TNF first, and why does the Actemra website state it should be used if the other drugs fail. I am worried they are putting the cart before the horse. I would love hearing your opinion on this matter. Thank you for taking the time to read this. PretzeladyView Thread
HI Scott, Thank you for responding to my problem. This study is sponsored by Bristol-Meyers Squibb and is divided into 7 different treatments. All but one has methro included, and each dose of the experimental drug is different. My rheumatoligist runs the study and gets paid for it. I have decided not to take part. Right now the pain is under control some, so I can live with it until I get a dibilitating flair again. IWhen I do, I am going to ask him about putting me on a safe biologic drug. I know there is some risk to all of them, but at least I will feel safer taking something that has been tested. I only hope I will be able to afford it. I know they are very expensive. By the way,the drug is named BMS-945429 and it will be administered to 406 subjects with approximately 25 of them from the United States. This drug may block a protein called interleukin 6, which is important in inflamationand may be responsible for the signs and symptoms of autoimmune disorders such as RA. Thank you again for your response. PretzeladyView Thread
I have been on Metho for about 12 years. About 5 years ago, I noticed my hair had thinned and I went through some significant hair loss. You could really see my scalp and I was horrified. I had read on this community that Folic Acid would help stop the hair loss. I talked to my rheumy about it and he prescribed 1mg a day of it. It has helped tremendously, but it didn't happen overnight. I noticed an improvement in about a year. It stopped falling out and I let it grow. By letting it grow, it appeared thicker. I also found a wonderful product called TOPPIK. You can get it in many shades to match your hair. You just shake it on dry hair where it is thin, pat it, then spray it with hair spray. It is made of natural keratin fibers. It works wonders and no one could tell it was in your hair. It can be purchased at Sallys or a similiar store, also on line. Once you put it in, it stays till you wash it. It costs about $25 and lasts a long time as you don't have to use much. I still use it and reccomend it to all my friends that are losing hair. I think between this product and the Folic Acid, you will definitely see an improvement.View Thread
I have been on methrotrexate for about 10 years. it never bothered my gastrointestinal system, but I only take 3 a week. When the pain is really bad, and I do have bad flare ups, I go see my rheumy and he gives me cortisone shots. I also take 1 mg of folic acid and 2.5 mg of predisone a day.
The problem is, this last bout I had with pain was really bad. My CRP was over 400 and it should have been 4. Now he tells me the methrotrexate isn't going to help me as my hands are starting to turn some. He runs a study group and he wants me to try out a drug they are testing. I think it is a biologic drug. This is not an approved drug and I am afraid to try it. It would all be free and they claim it is safe. I am on the fence as to what to do. I am a very young 76 year old. Have any of you tried a test drug? I would love to hear from you. I would love to have your opinion on if I should try it or not. Thank You. PretzeladyView Thread
Thank You to all of you nice people for responding to my call for help. After I finished my weeks supply of steroids, I went back to my rheumy. By this time I felt pretty good, so he decided not to put me on the Humira. He did bloodwork and put me on 2.5mg of steroids a day, which is only one pill. He said it is a real low dose. I still have to take my 3 mtx pills per week. He really wanted to up that dose but I really didn't want to as my hair got thin from it. Right now I feel good and decided not to take the steroids till I start to feel pain. My last bout of pain lasted 6 weeks in my hands, wrists and upper arms. Maybe I will go into a short remission. I am waiting to see what happens. I have to go back to my rheumy in 10 weeks to see how I am doing. If any pain starts, I will immediately start taking the steroids. Hope things are going well for all of you. It sure is nice talking to someone who can relate to what you are going through. Good Luck to all.View Thread
I have been on metx for 10 years with no problems at all except some hairloss. I take ibuprofen for pain, sometimes 4 at a time. My joints aren't turning much but lately the flares have been lasting longer. My rheumy gives me two to three shots at a time for pain and it really helps, but I feel it is a quick fix till the next time. I have been taking the shots for years in the joints that are hurting at the time. I am starting to be a wimp and do not want shots any more. He mentioned going on Humira to me. I really don't know what to do. All the side effects are scary. I have to do something as this last flareup I had lasted 6 weeks and I could hardly do my everyday chores and personal things. He put me on steroids for the week and I go back when they are finished. He wants to do bloodwork and discuss the Humira. sometimes I get shots about every 2 months. I have had them everywhere except in the hip. Thank you for your reply.View Thread