Thanks for the valuable post. RA can be tough to diagnose. Symptoms can mimic other illnesses, or they may flare, then fade, only to flare again somewhere else. Lab tests aren't perfect—you can test negative for RA factors and still have it. And X-rays don't show signs until later on. Another symptoms Carpal tunnel syndrome, which is marked by tingling in the wrist and hands. Dryness of the eyes, mouth, nose, throat, or skin. This can happen even in the early stages of RA, but it's unlikely to be the only symptom.