I will say that kratom was not the best thing to ever come across..I felt great on it.. Almost as if God himself came down from heaven and personally blessed me by his mighty touch..Now Kssziggy I however wasn't taking any other substance just the kratom... I didn't get depressed tell after the first 8 hours of my last dose.. Oh yes I said 8 hours the withdrawal was fast and very complicated.. As of today I have made it to day 4 still feel real tired and the restless leg syndrome is still present...The (RLS) was almost the first system noticed..Other than the walking from one room only to find yourself crying in the next..True story by far the craziest thing ever..But the (RLS) is still happening even on day 4 by far the (RLS) is the biggest pain in the butt..So Kssziggy I'm not sure what your friend is going through as far as taking antidepressants along with kratom..If anything I was more energized a real warm and fuzzy love life lets get er done kinda of affects while using kratom..I do know taking a large amount or a strong dose of kratom will make you very tired... I would suggest to anybody to stay away from the herb...View Thread