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I hate myself

I hate myself I hate everything about me I just want to die I'm fat I'm ugly I'm poor I live in the worst...

Posted by Nemesis123

0 Replies | Share this:I hate myself I hate myself I hate everything about me I just want to die I'm fat I'm ugly I'm poor I live in the worst...

I hate myself

I hate myself I hate everything about me I just want to die I'm fat I'm ugly I'm poor I live in the worst...

Posted by Nemesis123

0 Replies | Share this:I hate myself I hate myself I hate everything about me I just want to die I'm fat I'm ugly I'm poor I live in the worst...

Am I the only one?

Hi.. I have the fear that their is no afterlife, therefor I am only a child. I lied my age, yes, because I...

Posted by An_267877

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0 of 0 found this Tip helpful

0 Replies| Share this:Am I the only one? Hi.. I have the fear that their is no afterlife, therefor I am only a child. I lied my age, yes, because I...

Am I the only one?

Hi.. I have the fear that their is no afterlife, therefor I am only a child. I lied my age, yes, because I...

Posted by An_267877

Was this Helpful?

0 of 0 found this Tip helpful

0 Replies| Share this:Am I the only one? Hi.. I have the fear that their is no afterlife, therefor I am only a child. I lied my age, yes, because I...

Depressed

Hello. I didn't think I would ever have to go through this but yet here I am. Lately I have been feeling very...

Posted by An_267871

0 Replies | Share this:Depressed Hello. I didn't think I would ever have to go through this but yet here I am. Lately I have been feeling very...

Reply: Depressed 19 year old daughter

Hi Danie5, I'm so sorry that you've had to watch your daughter go through this. I completely understand...

Posted by editor_morgan

Hi Danie5,

I'm so sorry that you've had to watch your daughter go through this. I completely understand how helpless you must feel.

I really encourage you to read this story about a mother and daughter's journey through self-harm and and how they finally got the strength to get help. It is helpful to sometimes to read stories of people who have been through the same thing and to be reminded that you are not alone.

Someone who is self-harming needs immediate help, according to this article . I highly suggest that your daughter seeks support group therapy for her depression. Cutting is a symptom of an underlying problem and if it is never addressed then the symptom will continue. Read more about how to find a depression support group that's right for your daughter.

Yes, your daughter is an adult, but if she is a danger to herself then you do have options. It says here that when people just can't break the cycle through therapy, an inpatient program can help.

At WebMD, we want to help our members when they need it the most. Here is a list of crisis resources, hotlines, and web sites that may be of help if your daughter is ever in trouble. Please provide this list to your daughter, and tell her that in the case that she thinks she needs immediate help and cannot speak to a family member, a medical professional, or a member of the clergy, to please reach out to one of these organizations or dial 911 immediately.

Crisis Call Center
Phone: (800) 273-8255
Hopeline Network
Phone: (800) 422-HOPE (1-800-422-4673)
National Runaway Safeline
Phone: (800) RUNAWAY (1-800-786-2929)
National Suicide Prevention Hotline
Phone: (800) 273-TALK (1-800-273-8255)
Befrienders Worldwide
Resources and numbers by states and countries
Boys Town Hotline
Phone: (800) 448-3000
The Trevor Project
Phone: (866) 488-7386
Veterans Crisis Line
Phone: (800) 273-8255 Press 1
The Samaritans
Phone (In the UK and ROI): 116 123

Please be sure to keep us updated. We care about you and your family, and we are here for you ((hugs)).View Thread

Posted by editor_morgan

1 Reply | Share this:Depressed 19 year old daughter Hi Danie5, I'm so sorry that you've had to watch your daughter go through this. I completely understand...

Reply: Deteriating health, Mental and Physical

Hi needsomefun, Please let me share with you my favorite quote. "Happiness is beneficial for the...

Posted by editor_morgan

3 Replies | Share this:Deteriating health, Mental and Physical Hi needsomefun, Please let me share with you my favorite quote. "Happiness is beneficial for the...

Reply: problems

Hi daynas1234, I'm so sorry to hear that you've been going through this. Agoraphobia is such an...

Posted by editor_morgan

2 Replies | Share this:problems Hi daynas1234, I'm so sorry to hear that you've been going through this. Agoraphobia is such an...

Reply: Bipolar depression

Hi there and thanks for posting, Daynas1234 brings up a good point. Have you spoken to your doctor...

Posted by editor_morgan

2 Replies | Share this:Bipolar depression Hi there and thanks for posting, Daynas1234 brings up a good point. Have you spoken to your doctor...

Reply: I feel death is my only answer

hey i understand as i can see no end to it. maybe this is the way we are suppose to go? but it is hard to...

Posted by bigthecat

23 Replies | Share this:I feel death is my only answer hey i understand as i can see no end to it. maybe this is the way we are suppose to go? but it is hard to...

Reply: Depression

There are a number of places that you can begin to find support. The first is your primary care doctor. If...

Posted by atti_editor

1 Reply | Share this:Depression There are a number of places that you can begin to find support. The first is your primary care doctor. If...

Reply: Sad

It sounds like you are doing so many things right -- exercising, volunteering, socializing, keeping up with...

Posted by atti_editor

1 Reply | Share this:Sad It sounds like you are doing so many things right -- exercising, volunteering, socializing, keeping up with...

Reply: I need someone who understands

I am also depressed and have anxiety and agoraphobia where most the time i don>t leave the house and if i...

Posted by daynas1234

3 Replies | Share this:I need someone who understands I am also depressed and have anxiety and agoraphobia where most the time i don>t leave the house and if i...

Reply: My husband told me he'd wake up sometimes not reme...

No, my hubby was not prescribed any medications. And he hates taking them, too. I wouldn't think that seeing...

Posted by chteacher

3 Replies | Share this:My husband told me he'd wake up sometimes not remembering his name. No, my hubby was not prescribed any medications. And he hates taking them, too. I wouldn't think that seeing...

Drug metabolism

While I understand WebMD does not and can not dispense medical advice, I'm hoping there might be some insight...

Posted by An_267806

While I understand WebMD does not and can not dispense medical advice, I'm hoping there might be some insight or hypotheses advanced from the medical experts available here.

I appear to be what is alternately referred to as an ultra-extensive or ultra-rapid metabolizer. Following both an emergency appendectomy (midazolam administered, possibly with other meds) and a colonoscopy (midazolam and propofol as "twilight sedation"), I was informed both times that it was very difficult to keep me sedated. I have never had any notable sedative effect from any of the benzodiazepines, the so-called "Z drugs", antipsychotics, and even off-label uses of meds like hydroxyzine and dextromethorphan. I've had no response (favorable or negative) from many SSRI, SNRI, and tricyclic antidepressants. I also seem to have a considerable tolerance for chemicals such as ethanol and nicotine.

Of the many medications I've tried, I've found only two that have a demonstrable sedative effect, promethazine and off-label quetiapine. Both are quite effective somnifacients, but of little benefit to the constant exhaustion whenever awake. Nitrous oxide during dental procedures does have a calming effect without hallucinatory aspects, but only at exaggerated levels (as high as 80% mixed with 20% oxygen, or so I'm told).

Clearly, this has made it quite difficult to find depression medications that are effective. (By now, I'm fairly sure I qualify for the "refractory" definition of depression.) Venlafaxine and desvenlafaxine both introduce derealization (specifically, the "dolly zoom" effect some patients report), but no other NRI meds (such as desipramine) have ever been found to cause such effects.

After extensive research and a lack of answers from various physicians, I'm finding myself wondering if this is an issue of drug metabolism related to an issue with CYP deactivation or biodeactivation. If so:

â€¢ What options exist for testing of CYP function?

â€¢ If a genetic problem with CYP function is found, what options are there for treating it?

If CYP function seems an unlikely scenario, what other areas might be suggested for investigation?

Non-medicinal therapies (psychiatry, psychology, hypnosis, cognitive behavioral therapy, excercise, etcetera) have all been unsuccessful, and I'm becoming desperate for something that will be effective in this decades-long battle. Thanks for any observations or input you can offer!View Thread

Posted byAn_267806

0 Replies | Share this:Drug metabolism While I understand WebMD does not and can not dispense medical advice, I'm hoping there might be some insight...

early morning waking with panic

I am currently taking trintellix and xanax, prescribed by my internist. I have an appointment in a fe months...

Posted by chteacher

Take the Poll

What to do about early morning waking with panic

0 Replies | Share this:early morning waking with panic I am currently taking trintellix and xanax, prescribed by my internist. I have an appointment in a fe months...

Reply: what is wrong with me?

I, too, am 57. I am so sorry for all the health issues you are going through. I wanted to reply so when you...

Posted by chteacher

Take the Poll

Any help out there?

1 Reply | Share this:what is wrong with me? I, too, am 57. I am so sorry for all the health issues you are going through. I wanted to reply so when you...

Reply: Adult Bulimic Child with Lifelong Depression

I am sorry to hear this about your daughter. It sounds like she has multiple issues going on. Please don't...

Posted by cswilson

1 Reply | Share this:Adult Bulimic Child with Lifelong Depression I am sorry to hear this about your daughter. It sounds like she has multiple issues going on. Please don't...

Bipolar depression

Effexor causes me to sweat excessively from my head I am a women is there other medicine( took paxell went...

Posted by An_267785

0 Replies | Share this:Bipolar depression Effexor causes me to sweat excessively from my head I am a women is there other medicine( took paxell went...

Reply: Stomach Sinking Feeling

I have anxiety, and I often get that sinking feeling you are talking about; often it borders on nausea,...

Posted by magnusmalermann

2 Replies | Share this:Stomach Sinking Feeling I have anxiety, and I often get that sinking feeling you are talking about; often it borders on nausea,...

Reply: Masturbation

I am a male and have done my fair share of masturbation. It has never caused me back pain. However, I suppose...

Posted by An_267781

1 Reply | Share this:Masturbation I am a male and have done my fair share of masturbation. It has never caused me back pain. However, I suppose...

Reply: Medication problems

first of all I would question whether you preformed the drug test correctly The odds are so low of a pharmacy...

Posted by An_260948

2 Replies | Share this:Medication problems first of all I would question whether you preformed the drug test correctly The odds are so low of a pharmacy...

Reply: Depression and OAB-overactive bladder

Hi. I don't have OAB, but I did from 2004 to 2016 as long as I was on anti-depressants. During the day,...

Posted by magnusmalermann

1 Reply | Share this:Depression and OAB-overactive bladder Hi. I don't have OAB, but I did from 2004 to 2016 as long as I was on anti-depressants. During the day,...

Reply: How do I deal with memory loss caused by my depre...

Are you able to see a physician about your depression? If your mom came along, the physician could...

Posted by magnusmalermann

2 Replies | Share this:How do I deal with memory loss caused by my depression? Are you able to see a physician about your depression? If your mom came along, the physician could...

Reply: HELP

Hi. I have not heard of Celexa being used for overactive bladder, but I would not be surprised if it...

Posted by magnusmalermann

1 Reply | Share this:HELP Hi. I have not heard of Celexa being used for overactive bladder, but I would not be surprised if it...

Reply: Sinking feeling

Hi. This sounds like what happens to me when my anxiety acts up. I get anxious, and this makes my...

Posted by magnusmalermann

1 Reply | Share this:Sinking feeling Hi. This sounds like what happens to me when my anxiety acts up. I get anxious, and this makes my...

Depression and OAB-overactive bladder

I have OAB and I was prescribed IMIPRAMINE and told to take it at night because it does make you sleepy. It is...

Posted by k112233

0 Replies | Share this:Depression and OAB-overactive bladder I have OAB and I was prescribed IMIPRAMINE and told to take it at night because it does make you sleepy. It is...

Reply: Depression - help!

I feel u. Been on and off of them for about the same time and these last few weeks it's one thing after...

Posted by bigmeanmom

2 Replies | Share this:Depression - help! I feel u. Been on and off of them for about the same time and these last few weeks it's one thing after...

Reply: My 18 yr old hospitalized

Hi Kristenvic, I think the best thing you can do for her now is just be there for her and in case she's...

So, this is my life. And I want you to know that I am both happy and sad and I'm still trying to figure out how that could be.
- Stephen Chbosky

Posted by behapppy118

1 Reply | Share this:My 18 yr old hospitalized Hi Kristenvic, I think the best thing you can do for her now is just be there for her and in case she's...

Reply: Random rant, but can anyone relate?

don't know how you do it. maybe you could stay with your parents for awhile until you figure something out?

Posted by cabswrub

3 Replies | Share this:Random rant, but can anyone relate? don't know how you do it. maybe you could stay with your parents for awhile until you figure something out?